TABLE OF CONTENTS
For decades reviewers worldwide have been captivated by the ability of Medicinal Mushrooms To Break Down Organic Matter and Their Medicinal Use.
Specifically, The Research Has Focused on Bioactive Compounds of Interest containeted in mushrooms. You include Various Nutraceuticals Such as lectins, Triterpenoids, Polysaccharides, Phenolic Compounds, Flavonoids, Proteoglycans, and Ergosterol.
In This Inventory Is lentinan, Polysaccharide Found in Shiitake. The Compound You have attacted considerable attention from the Scientific Community Due to ITS Potential Impact on The Immune System.
WHERE DOES LENTINAN Come from?
Lentinan originates from the Shiitake Mushroom, a Mushroom Well Known to Gourmets and Natural Remedy Enthussa.
ITS NAME DIRECTLY REFLECTS THE LATIN CLASSIFICATION OF THIS MUSHROOM: Edodes lentinula, similar to how ganoderan corresponds to Ganoderma lucidum Or Grifolan to Frondosa tap.
Shiitake, Which Often Grows on Tree Trunks, is a lot of than just a culinary ingredient. STIs Active biomolecules, Including slow, are now the focus of exciting research aimed at understanding and usersing its properties.
>> For More Information on Shiitake, See Our Artle on Shiitake.
Lentinan: Shiitake Polysaccharide
Shiitake’s lentinan Belongs to the Polysaccharide Family. These Molecules are contained in all basidiomycete fungi, Among Which it is Found. More spectifically, lentinan Belongs to the Beta-Glucan Subfamily.
Elucidated in the 1970s, The Primary Structure of Lentinan Consists of A Backbone of Glucose Units Linked by Beta-Glycosidic Bonds at 1.3 and Branching at 1.6. The Numbers corresponding to the way the units are Linked Together.
Ultimately, The Specific Molecular Structure of Lentinan Consists of 5 Glucose Units Linked at 1.3 with 2 Glucose Branches at 1.6. Although β-Glucans Are Common, There are meaning variations in their biological activities due to their different structures.
The Importance of Polysaccharides in Mushrooms
Lentinan and Polysaccharides Are of Vital Importance for the Survival of All Fungi and Are at The Heart of Their Life Process.
- Movements: to expand rather Than "Move", Fungi Develop Hyphae. Movement is Stimulated by the Production of Hyper-Amplified Polysaccharides.
- Nutrition: Polysaccharides are present during the Degradation of lignocellululosic material and contribute to the production, movement and activity of enzymes.
- Communication: In The Cell Wall, Polysaccharides Form Networks Which, During Cell Division and Fungal Growth, Are used as Channels for Cell Communication and Signalling.
- Protection: The witness of polsaccharides in the hyphae improper Mechanical Resistance and Thus Protects The Cells from External Agrassions.
The Biological Actions of Lentinan
A Review of the Scientific Literature Reveals Two Facts: Firstly, Beta-Glucans Are Among The Compounds Most Studied by The Scientific Community; Secondly, This Compound is the beta-glucan that has been MostSively Studied. VARIO STUDIES, WHOTHER In vitro, In vivo or clinical, are helping to Shed Light on The Biological Mechanisms of this compound.
Immunomodulatory Action
Research shows that slow plays a crucial role in Regulating the Immune System. By binding to Various Membrane Receivers Such As Tlr2/4/6/9, Decin-1, as well as the complement receiver cd11b, β-glucan Activates Signalling Pathways Such As Mapk-NfκB and Syk-PKC. These activates stimulate immunocytes such NK Cells, Macrophages and T Cells (See Figure Below).
Since the 1980s, Knowledge of the Immunomodulatory Mechanism has underpinned The use of lentinan in the Chinese and Japanese Health Systems For the Treatment of Certain Ailments.
In addition, other studies highlight the Cytotoxic potential Of this compound, Although Further Clinical Research is Needed to Investigate This Further.
Hifas da Terra: Biotechnology Company
As a Biotechnology Company Specialising in Medicinal Mushrooms, We Pay Playa Attention to Fungal Extracts. For Each of Them, We Are Committed To Highlighting The Bioactive Molecules of the Mushrooms by Clearly Specifying Them on Our Labels. For All Our Products Including Shiitake Extracts, We Specifically Display The Quantity Present ..
Learn More